Bill and William Shatner comically riff on the last acceptable prejudice, the spectrum of human sexuality, bad crowds in comedy, the making of Religulous, and the origin of the universe.

Bill and Quentin Tarantino randomly riff on movies that make no sense, the developmental stages of babies, Quentin's love of Politically Incorrect, the Once Upon a Time in America bromance, and that time Quentin visited Bill backstage in Austin.

Bill Maher and Judd Apatow randomly riff on whether humans will merge with machines, Maude Apatow being in Euphoria, why Judd refuses to take a DNA test, how Judd was chased for smoking weed, and why George Carlin still trends on Twitter.

Bill Maher and Bella Thorne randomly riff on Bella's love of Lady Deadpool, Bella's politically incorrect dog naming process, distractions during sex, Bill tries to help Bella with her anxiety, and how Bella was signed to be a model while she was still a fetus.

Bill Maher and Piers Morgan randomly riff on the Meghan Markle controversy, how the Brits are becoming as sensitive as Americans, why Yoko did not break up The Beatles, successful civilizations becoming weak, and how athletes like Naomi Osaka are celebrated more for quitting than winning.

Bill Maher and Freddie Gibbs randomly riff on Bill's emergency landing in Gary, Indiana, Freddie's Grammy nomination, Bill Cosby, things black people invented, and Bill and Freddie going on tour together.

Bill Maher and Dr. Drew Pinsky randomly riff on the good old days of office romances, Dr. Drew's secret to living longer, the feminization of men, surviving the woke vortex, the Coolidge Effect and the love lives of roosters.

Bill Maher and Mike Tyson randomly riff on why Mike flies Jet Blue, how everybody wants to beat up Jake Paul, pigeon racing, the best punch known to man, and the tragedy of Amber Heard and Johnny Depp.

Bill Maher and Killer Mike randomly riff on reverse interventions, Bill and Mike's excellent adventure in Atlanta, the etiquette of making it rain, the poetry of rap lyrics, what's worse for you than liquor, how Mike's mom encouraged him, and Bill's college job.

Bill Maher and Howie Mandel (new show "Bullsh**t the Game Show" on Netflix) randomly riff on how close Howie is to becoming Howard Hughes, the childhood trauma that gave him OCD, why Bill jumps on a trampoline every day, the impact of luck on a show business career, cancel culture and the war on comics, Howie's first time on stage and the birth of his famous rubber glove bit, and saying goodbye to Gilbert Gottfried. Stay to the end and see Bill extend a very special invite to Howie.

Bill Maher and comedy creator Adam Waheed randomly riff on feeding the beast that is Tik Tok, how Bill creates his stand-up act, Bill teaches Adam about the ACLU and NATO, the process of learning things and Bill's "Gazpacho moment," a big reason for the conflict in the Middle East, and why Bill will never have children.

Bill Maher and Jimmy Kimmel randomly riff on why Bill hates hockey, how Bill's advice could have cost Jimmy millions, the Conan O'Brien-Jay Leno feud during the late night wars, why Jimmy loves David Letterman, Jimmy's high profile friends, and how Jimmy saw Bill and Jerry Seinfeld in concert when he was in college.

Bill and Sammy riff on rock and roll excess, the upbringing and the heartbreak that drove Sammy to be a rock star, the technology that would have helped Bill talk to girls when he was younger, how to survive fights when you're married, Sammy and Eddie Van Halen making peace at the end, and how Quentin Tarrantino put Sammy's tequila brand in his movie.

Bill Maher and Adam Carolla randomly riff on the war that is show business, how you know when you're too high, how kids used to be scared of their friends' dads, why messing up your kids ruins it for everyone, government red tape making life impossible, and the joke that Adam couldn't tell.

Bill Maher and John McEnroe randomly riff on how Bill would go "John McEnroe" on bad comedy audiences in the early days, what happened to the one good linesman in tennis, what percentage of cops are good, where John once ranked on the "most hated man in the world" list, comparing Donald Trump to a certain dictator, getting real about Joe Biden and what John texted to Novic Jokovich about his decision at the Australian Open.

Bill Maher and Cedric the Entertainer randomly riff on the Kings of Comedy golf tour, how Bill Clinton is a master multi-tasker, which famous people were wrongly canceled, why Jesse Jackson and Al Sharpton called Cedric about his role in The Barbershop, the thing that annoys Bill the most at Real Time, how much Bill actually reads, the definition of addiction, and the freedom of saying exactly what you think.

Bill Maher and Lisa Kudrow randomly riff on bad behavior on sitcom sets, the stupidest thing Bill ever did in show business, Bill's favorite show of Lisa's (it's not Friends), how The Andy Griffith Show made Bill join PETA, Lisa's most awkward audition ever, and whether or not you have be insane to be a great actor.

Bill Maher and YouTube sensation Hannah Stocking randomly riff on the "ok" symbol and what it means now, being friends with your parents, Hannah's love of TED talks, why dating millennials is a huge challenge, which alcohol doesn't give you hangovers, how the concept of soul mates is stupid, and why Bill will never have kids.

A belated Happy Birthday to Kris Jenner as Bill Maher and Kris randomly riff on Mexico and the origin story of Kendall's 818 Tequila, why they wouldn't want to go back in time and have to start over, the value of having children young, Bill's door to door salesman job, the joy in Kris and her family finding success, how Hulu has reinvigorated the Kardashians TV show, and how haters are like germs.

SNL alum Kevin Nealon hangs out with Maher.

Actor/Director Sean Penn hangs out with Maher.

Bill Maher and Fran Lebowitz talk travel nightmares, their least favorite feral creatures, outdoor dining and New York City rats, who always wins in politics, city living vs. country living, Bill's Tik Tok obsession, why Fran is stickler for grammar, the effect of being on Netflix, and her friendship with Martin Scorcese.