Joaquín Guzmán Loera receives a visit from his second wife Graciela. After Amado’s death, Benjamín and Ramón Avendaño become the new drug-trafficking lords.

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El Chapo asks Chito for help so that he can escape from prison in exchange for making him part of his team. Conrado is looking for Mirta to offer his services against narco and thus be able to put himself back into the government.

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Joaquín Guzmán Loera sets a trap for Raciel Cárdenas to be captured and take over the territory of Nuevo Laredo. 'El Chapo' and 'La Federación' begin a war against 'El Cano' and the bloodthirsty army of 'Los Emes'.

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El Chapo', Joaquín Guzmán Loera heads the funeral of his brother 'El Pollo', murdered by 'Chente' and Raciel. 'El Cano' invades the territory of 'La Federación' to kill the men of 'El Chapo'.

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'El Chapo', orders 'Don Sol' to avoid the arrival of Andrés Labrador to the presidency of Mexico, because he fears that his business will end with him.

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Joaquín Guzmán Loera promises 'Don Sol' to end the failed war against drug trafficking and pacify the country. Thousands of innocent people suffer the terrible consequences of the clashes between 'The Federation', 'The Emes' and 'Chente'.

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Teens and young adults are kidnapped in Nuevo Laredo and forced to work for the warring cartels. A mother travels to Culiacán to search for her child.

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Arturo Bernal Leyda acts as peacemaker between Joaquín Guzmán Loera and 'El Cano' and 'Chente'. 'El Chapo' betrays the two fundamental partners of 'La Federación' to get one of his sons out of jail.

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Joaquín Guzmán Loera orders the hunt of Arturo Bernal Leyda, who attacks him in his territory of Sinaloa with the help of 'El Cano' and 'Chente'. Nazario Moreno walks out of 'La Federación' after 'El Chapo's new war.

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Pain gets hold of Joaquín Guzmán Loera after the murder of his son, 'El Moreno', so he leaves Ismael in charge of the war. 'Don Sol' fears that 'El Cano', 'Chente' and Arturo Bernal Leyda might use 'El Chapo's weakness in their favor.

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Back in Culiacán with renewed resolve, El Chapo sets out to eliminate his enemies one by one. Don Sol gets a dream offer, but with a strict condition.

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