In the Season Two premiere, Spawn's nightmares reveal that Al Simmons' killer was his mercenary ex-partner, Chapel. CIA chief Jason Wynn tells Chapel to find a cache of stolen guns before they are uncovered and traced back to him.

Spawn is tortured by dreams of his former wife Wanda now sleeping with his onetime best friend Terry, and the manipulative Clown fuels the fire by trying to get Spawn to blame Terry for stealing his wife.

When a pack of drug dealers start terrorizing the homeless in Rat City, Gareb pleads with Spawn to get rid of them--initially to no avail. But after a ruthless killing, Spawn takes charge, 'eliminating' all the dealers except the leader.

With a serial killer on the loose, Wanda's search for her husband Terry hits a detour when Wynn's men follow and corner her. Appearing on the scene to eliminate the agents, Spawn allows Wanda to see him for the first time--but she's horrified.

While Lisa Wu is investigating the murders of two other reporters, Terry is arrested by the police. Wynn blames Merrick for all his recent problems finding Terry; as punishment, he sends another agent to kill Wanda and Cyan.

In the Season Two finale, Spawn takes the fight to Wynn, telling him that he is coming for him at midnight. Seeing his schemes beginning to crumble, Wynn attempts to have his agents kill Lisa Wu as she draws closer to the truth.