Shaun and Lea's upcoming engagement party has everyone in a festive mood after their return from Guatemala. Meanwhile, a young single mother learns her son may have contracted his cancer from a surprising source, and Mateo finds out if his previous issues in America will be resolved.

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Shaun and the team race to save a pregnant woman's baby and find her current situation as a convicted felon complicates it even more than they realize; the hospital takes on some unexpected changes that the staff is not prepared for.

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Shaun confronts Salen about the many changes she has implemented since coming on at St. Bonaventure, and Glassman is forced to accept his new role at the hospital.

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Dr. Shaun Murphy and the team treat a young girl whose father's personal research complicates their treatment plans. Meanwhile, Dr. Park, Dr. Reznick and Dr. Lim's patient refuses a life-saving lung transplant despite having a family donor.

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Dr. Park and Dr. Murphy treat an elderly Asian man brought to St. Bonaventure by his daughter after being the victim of a hate crime. In addition, Lea goes behind Shaun's back to help raise his negative patient satisfaction scores.

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Dr. Shaun Murphy and Dr. Alex Park must grapple with a life-and-death decision and decide between saving one patient over another. Meanwhile, Dr. Morgan Reznick goes a little too far in her attempt to win Salen's favor.

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After visiting a possible wedding venue, Shaun and Lea happen upon a terrible car accident and discover Alma, a young pregnant mother who has been badly injured and needs immediate medical attention. Back at St. Bonaventure, Alma's condition worsens, and Shaun and Drs. Lim and Jordan are forced to deliver the baby prematurely. Meanwhile, Dr. Glassman is apprehensive when a figure from his past reaches out for help.

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Shaun is forced confront Lea about their relationship and determine what he really means to her; the team debates about plastic surgery; Lim hopes to expose Salen's cover-up over an infant's death

In an effort to please Salen, Andrews takes on a high-profile case and assigns Shaun and Allen to help perform a risky surgery to restore the voice of a famous pop star.

Salen takes extreme measures when she learns that the surgical staff have joined Lim's efforts against her. The team treats a liver transplant patient whose organ donor unwittingly gave him cancer.

A personal connection threatens Shaun's objectivity.

Drs. Lim, Park and Wolke treat a woman with Valley fever and discover a secret she has been hiding from her fiancé. Meanwhile, Drs. Murphy, Allen and Andrews treat a 45-year-old virgin and help her make a big decision about her life.

While Drs. Lim, Murphy and Wolke help a teenage biohacker, Drs. Morgan, Park and Jordan treat a young woman who wants a controversial surgery to treat her depression and chronic pain.

When someone mistakenly brings a hallucinogen-laced dish to the hospital's company potluck, much of the hospital staff and doctors are incapacitated forcing Murphy, Glassman and Allen to take on all of the hospital's cases.

Dr. Andrews treats a foster kid for injuries from a fight in the group home. Shaun and his team look to Lea for expertise with cars and auto repair for a patient whose iron lung broke.

As Shaun and Lea head toward their wedding day, a documentary filmmaker showcases their special relationship.

Sophie takes Lea for a day full of luxurious wedding planning. After a near fatal oversight, Dr. Lim investigates what is behind nurse Villanueva's unprofessional behavior.

Shaun and Lea make a big life decision and are pleasantly surprised by the support they receive from their friends at the hospital; Asher struggles to accept that he and his father may never truly understand one another.