5x1 – Episode 1
While in a self-imposed exile in the Yukon as a prospector at the end of the Gold Rush, Murdoch prospects for gold as in his absence Crabtree works on a Toronto homicide.
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5x2 – Episode 2
Detective Murdoch must tread carefully when he pursues a Catholic suspect in the murder of an Alderman, killed during the attempted assassination of the city's Protestant Mayor.
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5x3 – Episode 3
When Detective Murdoch investigates a series of deaths linked to an exhibition of Egyptian antiquities, Constable Crabtree is convinced a mummy's curse is to blame.
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5x4 – Episode 4
While investigating an explosion, Detective Murdoch infiltrates an anarchist group lead by American labour organizer Emma Goldman.
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5x5 – Episode 5
A talented young opera singer, who is being mentored by the show's diva as her understudy, is poisoned at a rehearsal with Brackenreid, a great admirer of the soprano,, in charge of the investigation.
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5x6 – Episode 6
Detective Murdoch suspects the ambitious inventor of an electric vehicle murdered an associate who stood in the way of his plans to compete with Henry Ford.
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5x7 – Episode 7
When a demure, engaged librarian, who led a double life a a prostitute in a local saloon, is found strangled, Anna Fulford, still on the run from the Black Hand, helps Murdoch in his murder investigation.
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5x8 – Episode 8
When another prostitute from the Devil's den is strangled, Murdoch discovers they both sang in the same choir, and there is no shortage of suspects.
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5x9 – Episode 9
An obnoxious but brilliant inventor who is thoroughly disliked by his colleagues wins First Prize at an 'invention convention' but is shot in the forehead by an unknown killer as he accepts the award.
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5x10 – Episode 10
Detective Murdoch is called out to a remote house when one of the guests, Jacob Oliver, is murdered. There he finds Dr. Grace who was also a guest in the house. It's quickly apparent to Murdoch that something is wrong and he finally learns the truth: everyone there was playing cards to see who would have the privilege to die. Dr. Grace and her friends have been seeking to glimpse the afterlife by inducing death and then bringing the person back to life. There is no doubt one of the card players was killed however - he has a piece of metal in his throat. Back at the ...
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5x11 – Episode 11
The kidnapper of a young girl leaves a talking doll in her room which is diabolically designed to lead Murdoch on a quest that is designed by a manipulative, enigmatic and vindictive criminal from the detective's past.
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5x12 – Episode 12
Two hockey teammates have a locker room altercation, and one of them is injured with a head wound. He does not go with his teammates for a post-practice drink and is later found dead in the locker room from a second blow to the head.
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5x13 – Episode 13
As New Year's Eve and a new century approach, a seemingly unbalanced man who claims to have visited the future in a time machine prevents an accident and murder that he knew were going to happen.
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