Will Halstead returns to Med to help Goodwin with a secret investigation. Archer and Charles deal with twins who insist on being identical inside and out. Stevie and Dylan treat a young patient with sickle cell anemia.

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Vanessa and Archer disagree on how to handle the victim of a motorcycle accident; Scott and Charles deal with a UNICEF negotiator with repressed trauma; Hammer and Halstead treat a high schooler with Addison's disease and a clingy mother.

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Scott and Halstead deal with a dishonest patient whose lupus is in remission; a wealthy donor makes inappropriate advances toward Hammer; Vanessa, Marcel and Charles try to convince a young woman to have life-saving surgery.

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Charles helps Dylan with a longtime patient who was recently diagnosed with schizophrenia. Stevie, Maggie and Vanessa investigate the legitimacy of a cancer patient's diagnosis. Crockett is caught off-guard. Will pitches a new medical technology.

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Dylan and Charles treat patients suffering from Glass Child Syndrome and misdiagnosed ADHD. Crockett has to navigate hospital politics when he cares for the daughter of a transplant surgeon. Will and Stevie must lay egos aside to help save an elderly patient.

Stevie's personal and professional worlds collide when her mother becomes her patient. Dylan's history with the father of a patient interferes with his perception of a case. Crockett's allegiances are challenged when his patient's liver is a potential match for one of Dr. Blake's patients.

Marcel helps Blake replace a patient's liver; Taylor tries to prove herself; Halstead continues to pursue the truth about Cooper; Choi gets closer to returning to life in the ED.

Dylan's loyalty to Med and the police department is challenged when an old family friend and veteran cop exhibits concerning behavior. The annual random drug testing puts a doctor's career in jeopardy.

The outcome of Will's investigation weighs heavily on his mind as he and Dylan work to save a four-month-old patient. Stevie and Vanessa both struggle to keep their secrets. Crockett and Blake work with Abrams to save a patient in need of a liver transplant.

In the aftermath of the Vas-COM scandal, Goodwin clashes with the hospital's new compliance officer. Crockett and Blake try to save a patient whose son has severe autism. A patient's son lies to his father about his diagnosis.

Crockett and Blake clash with Randall when a famous alcoholic football player needs a liver transplant. Dylan is reluctantly reunited with old friends when their son breaks his arm. Stevie and Charles work together when a patient falls ill after back-alley plastic surgery.

Will and Stevie get stuck in the middle of a marital face-off. Dr. Blake's entire surgical team mysteriously collapses during a liver transplant. Charles encourages Ethan to reconcile with his father.

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