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5x1 – Famous Last Words
5x2 – All in Vein
5x3 – Truth or Dare
5x4 – Suspicious Minds: Part 1
5x5 – Suspicious Minds: Part 2
5x6 – A Dignified Exit
5x7 – Position of Trust
5x8 – Preservation
5x9 – Black and Blue
5x10 – To the Bone
5x11 – Points of View
5x12 – Childsplay
5x13 – A Question of Priorities
5x14 – Food for Thought
5x15 – An Early Frost
5x16 – Numb
5x17 – With This Ring
5x18 – Faking It
5x19 – Call Me the Wanderer
5x20 – A Tangled Web
5x21 – Real Tonic
5x22 – Deliverance
5x23 – Second Class Ticket
5x24 – Jimi Hendrix Is Dead
5x25 – To Be or Not to Be
5x26 – Cave Man
5x27 – Baby Blues
5x28 – Mar-Cel Wave
5x29 – Still Crazy After All These Years
5x30 – Silent World
5x31 – A Woman's Work
5x32 – Teenage Kicks
5x33 – More Than a Job
5x34 – A Soldier's Lot
5x35 – When the Bough Breaks
5x36 – Tunnel Vision
5x37 – Send in the Clones
5x38 – All the Lonely People
5x39 – The Dragon
5x40 – Zero Tolerance
5x41 – Junk
5x42 – Different for Girls
5x43 – A Life of One's Own
5x44 – Born Again
5x45 – Gravy on That?
5x46 – No More Pain
5x47 – As Time Goes By
5x48 – An Honourable Man
5x49 – Nothing But the Truth
5x50 – Twice Shy
5x51 – Fifty-Fifty
5x52 – Stone Walls Do Not a Prison Make
5x53 – A Taste of Possibilities
5x54 – Drinking Games
5x55 – Doctors Are from Mars
5x56 – Forget Me Not
5x57 – Donations
5x58 – Mother Love
5x59 – Faking the Dead
5x60 – The Road Sweeper
5x61 – Too Little Too Late
5x62 – Give It Up
5x63 – Babes in the Wood
5x64 – Mr Punch
5x65 – Keep on Running
5x66 – In Loco Parentis
5x67 – Keepsake
5x68 – Physician Heal Thyself
5x69 – A Civilised Arrangement
5x70 – Fugue State
5x71 – Caught in the Web
5x72 – Voice of Reason
5x73 – Payback
5x74 – No Thugs in Our House
5x75 – Really Ill
5x76 – Good Grief
5x77 – The Foundling
5x78 – Assisted Passage
5x79 – Grievous Loss
5x80 – Name and Shame
5x81 – Put a Smile on Your Face
5x82 – Nothing to Fear But...
5x83 – Encountered Briefly
5x84 – Turning a Blind Eye
5x85 – You Only Have to Ask
5x86 – Lucky Man
5x87 – Loose Ends
5x88 – Conventional Warfare
5x89 – Driving Me Mad
5x90 – Food Glorious Food
5x91 – Collateral Damage
5x92 – Fat Lies

Receptionist Carolina Shaw dies from injuries resulting from a tanker explosion.

5x93 – All an Illusion
5x94 – If You Don't Know Me by Now

Dr. Brendan McGuire and Julia Parsons finally marry.

5x95 – Unlike Father, Unlike Son
5x96 – Docwatch
5x97 – Emotional Fallout
5x98 – In the Blood
5x99 – Who Goes There
5x100 – Roots
5x101 – No Refund
5x102 – To Have Not
5x103 – Rufus
5x104 – Love Hurts
5x105 – Slippery Slope
5x106 – Blackout
5x107 – Disclosure
5x108 – Today's the Day
5x109 – Appearances
5x110 – Terminally Uncool
5x111 – The Time Is Right
5x112 – Nothing Like Home Help
5x113 – Billie
5x114 – Aftershock
5x115 – Alpha Male
5x116 – Survival of the Fittest
5x117 – Now You See Me...
5x118 – Cut Loose
5x119 – Flashbacks
5x120 – Prodigal Child
5x121 – Love on the Rocks
5x122 – How's This My Problem?
5x123 – Impact
5x124 – Caught in the Middle
5x125 – Doppelgänger
5x126 – A Red Light Means Stop: Part 1
5x127 – A Red Light Means Stop: Part 2
5x128 – Mexican Way
5x129 – 'Til Death Do Us Part
5x130 – Time on Your Hands
5x131 – Deep Prejudice
5x132 – Back to Basics
5x133 – Trouble at the Bank
5x134 – Every Dog Has Its Day
5x135 – A Weight on Her Shoulders
5x136 – The Decision
5x137 – It's a Family Affair
5x138 – A Job for Life
5x139 – The Wrong Body
5x140 – The Caring Profession
5x141 – Keeping the Peace
5x142 – An English Woman's Home
5x143 – Mixed Blessing
5x144 – Keep It in the Family
5x145 – Under My Skin
5x146 – Pain Barrier
5x147 – Assumptions
5x148 – The Drugs Don't Work
5x149 – Say a Little Prayer
5x150 – The Measure of a Man
5x151 – Happy Pills
5x152 – Play It Again, Mac

Mac receives an award and is interviewed on Letherbridge radio. He looks back at his time with the practice.

5x153 – Odd One Out
5x154 – End of Innocence
5x155 – Where Shadows Never Fall
5x156 – The Long and Winding Road
5x157 – Out on Loan
5x158 – Solvent
5x159 – Four Walls
5x160 – Nature's Way
5x161 – Twins
5x162 – Unspeakable
5x163 – Dressing Down
5x164 – The Forgotten Warrior

Jude discovers she's pregnant, but who's the father?

5x165 – A Fresh Start

A desperate Susie Lucas kills herself in prison.

5x166 – Counting the Days
5x167 – Art of Noise
5x168 – Cold Cuts
5x169 – Best Behaviour
5x170 – Getting the Ride
5x171 – A Whiff of Sulphur
5x172 – Crescendo
5x173 – All I Want for Christmas
5x174 – House of Cards
5x175 – Look Ma, No Hands
5x176 – Last Minute Nerves
5x177 – Dead Man Talking
5x178 – No Pain, No Gain
5x179 – No Fury
5x180 – Wheels of Destiny
5x181 – Home Alone
5x182 – The Miracle
5x183 – A Recipe for Disaster
5x184 – Easy Come, Easy Go

'Mac' goes off with Liam to spend some time with him in Canada.

5x185 – The Good Guys Club
5x186 – Hidden Harm
5x187 – No Angel
5x188 – Look Both Ways
5x189 – A Late Flowering
5x190 – Repeat Prescription
5x191 – Testimony
5x192 – Talk to Me
5x193 – Spiked
5x194 – Granny's Little Helper
5x195 – Bald Facts
5x196 – Selling Souls
5x197 – The Children That Suffer
5x198 – Baby Doc
5x199 – Blue
5x200 – Stranger Than Fiction
5x201 – The Final Curtain
5x202 – Neighbourly
5x203 – My Stepmother the Alien
5x204 – Like Father
5x205 – Getting On
5x206 – Two Can Play: Part 1
5x207 – Two Can Play: Part 2
5x208 – Checking Out
5x209 – One Man's Meat
5x210 – Amy's Social Worker
5x211 – Amy's Mother
5x212 – Amy's New Home
5x213 – Amy's Father
5x214 – Amy
5x215 – Acting Out
5x216 – Stuck in the Middle with You
5x217 – Inner Circles
5x218 – First Impressions
5x219 – Siege Mentality

The Doctors are held hostage, and Jerry gets shot when a siege occurs inside the surgery.

5x220 – About a Boy

Mac returns from Canada to find chaos and death at Riverside following the siege. Faith mourns the death of Jerry.

5x221 – Odds On
5x222 – Internal Affair
5x223 – Close to My Heart
5x224 – Turning Back the Clock
5x225 – Four Year Itch
5x226 – The Birds and the Bees
5x227 – Holding the Baby
5x228 – Room 101

The doctors all go to a team building session in Room 101, to boost morale following the siege.

5x229 – Run Baby Run

The doctors organize a charity fancy dress fun run on behalf of The Haven. Ben declares his love for the sexy Jude, but she decides to run off to Glasgow to have her baby. Everyone's sad.

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