When Dr. David Keel's fiancée is murdered by drug smugglers, the distraught physician swears to avenge her death by bringing the criminals to justice. He's aided in his quest by an elusive character who calls himself John Steed.

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Steed infiltrates a heroin-selling gang to get the evidence needed to convict Dr. Keel's fiancée's murderer. Dr. Keel discovers a rival gang has hired an assassin to kill Steed.

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Steed impersonates a master forger to get evidence against a gang of vicious criminals. Steed well-laid plans are thrown for a loop when the forger's girlfriend shows up demanding to see him.

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Dr. Keel poses as the missing husband of one of his patients and is shot for his troubles. A murderous anesthesiologist plans to finish the job by tampering with Dr. Keel's oxygen during a minor operation.

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A General fakes his own death and arranges his daughter to be kidnapped in an attempt to thwart his wife's plan to grab his entire fortune. Unfortunately, the girl falls into the wrong hands and needs to be rescued by Steed.

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Dr. Keel rescues a girl who tries to commit suicide by jumping into the Thames River. He discovers that the young lady is a trapeze artist with a visiting circus and foreign agents seek to capture her in order to force her father, a defecting scientist, to return to his country behind the Iron Curtain.

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While investigating a gang of diamond smugglers, Steed is drugged and finds himself accused of a hit-and-run accident.

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An immigrant worker in England on a forged passport picks up a radioactive isotope by mistake. Unless he's located quickly, he and anyone near him will suffer from radiation poisoning. The worker thinks the police are pursuing him because of his being an illegal alien and does his best not to be captured.

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Steed investigates a series of arson cases. He finds a clue that the next victim will be a hairdressing salon on the verge of bankruptcy. Carol is snooping around the salon at Steed's behest when the building explodes.

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Frank Preston is released from prison with only one thing on his mind - the recovery of 100,000 pounds that he hid after his final robbery. Frank isn't the only one after his ill-gotten gains - he's trailed by two thugs, a scheming wife and John Steed.

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In order to get evidence on a ring of criminals who specialize in blackmailing civil servants, Steed allows himself to be compromised in a Soho strip club.

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Dr. Keel rescues a dancing instructor who nearly died from gas asphyxiation. When he returns to check on his patient, the police arrest the doctor for murder. It seems that the doctor's scarf had been used to strangle the unlucky young woman.

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When Dr. Keel attends a conference in Switzerland he is arrested for murder. The police also discover a microdot containing secret information that Keel was unwittingly transporting.

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In order to smash a gang who specialize in jail breaking, Steed plays a prisoner with plenty of money and a desperate need be sprung from prison.

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Sir Thomas Waller disapproves of his daughter's choice in boyfriends and hires a criminal to scare off an unwanted suitor. Keel and Steed rescue the swain from the criminal's henchman and discover a clue to an extortion plot.

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After an assassination attempt on Dr. Keel's friend, a pro-Western African leader, Keel investigates the man's secretary, while Steed flies to Africa to search for the conspiracy's roots.

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When a government agent dies at a secret shipyard used to build submarines, Steed discovers foreign spies had arranged for the "accident."

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Dr. Keel discovers that a man's serious injury is a dangerous bullet wound and the injured man may be linked to a recent diamond heist.

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Dr. Keel agrees to help the daughter of an old friend find her missing roommate. He traces the girl to the seamy underworld of prostitution.

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Top-secret documents are disappearing, and Steed trails them to a tawdry fairground in Southend. He's captured, hypnotized and left bound in a train tunnel to await his fate.

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While assisting hurricane victims in a remote Mexican village Dr. Keel treats a number of food-poisoning cases. He discovers that the vegetable oil the villagers have been given to cook with is actually hydraulic-fluid.

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A foreign monarch visiting London to sign a oil deal is targeted for assassination by dissidents from his native land.

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Steed and Keel confront a group of British fascists after discovering a Nazi war criminal frozen in a cryogenics experiment.

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When a revolutionary, but experimental, vaccine is stolen from a top-secret laboratory and a volunteer who was administered a dose dies, Keel and Steed agree to be human guinea pigs for the next test.

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A businessman struggles to sell a load of bananas before he dies from heart failure.

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Steed is sent to research facility when a scientist developing a radiation-proof material dies of radiation.

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