The lovely niece of a Korean War veteran is killed with a blow to her neck, and Mannix looks at evidence that suggests an ex-member of his old army unit murdered her.

Mannix has an ulterior plan when he's charged with grand theft, gets his licensed suspended, and becomes a bodyguard for a female crime boss.

Mannix tries to find a black former boxing champion, suspected of murdering a briber that corrupts young fighters.

Someone has been making threatening telephone calls to Joe Mannix, and this mysterious person begins to take shots at him, too -- one of which cuts down Joe's friend Barry Nolan, who runs the photography shop across from Joe's office. That incident brings Joe into a chance encounter with renowned magazine photographer Jill Packard, who eventually begins a friendship with him. But Joe begins to suspect that there's more to the threats than someone who just has a grudge against him, when one of the shots nearly hits Jill, too.

Mannix is hired by the sister of Geoffrey Paradine, a college student who has disappeared. As the episode opens, Mannix is taken off the case because she claims to have found him. Then she admits that although Paradine has contacted her, she believes that her brother is still in trouble. But as he continues to search for Paradine, Mannix starts to have strange hallucinations -- the first symptoms that someone has poisoned Mannix with a slow-acting toxin that will eventually kill him unless an antidote can be found.

A group of prisoners on death row in a prison near Lawson City stage a takeover, taking as a hostage a guard named Charlie Keefer, who is a friend of Joe Mannix. The prisoners demand that Mannix come to see them, where they tell Mannix that one of their number, Carl Dancik, is innocent, and that they want Mannix to re-open his case. Dancik was convicted of the murder of an old girlfriend, but claims he was framed for the crime. With only a few days to turn something up, Mannix turns to another old friend in Lawson City, award-winning newspaperman Frank McGill, to see ...

Victor Brady, a leader in the electronics business, runs up a gambling debt of nearly $250,000 to a Las Vegas casino. Brady's private plane disappears from the radar on its way back to Los Angeles, but after his memorial service, his widow hires Joe Mannix to look for him, claiming that her husband is still alive and contacting her for help in raising the money to pay the casino. His investigation leads Mannix to that casino and the assorted people who work for it and who knew Victor Brady.

Peggy is recovering from a bullet wound in the hospital when she starts to fall in love with a patient who is the target of an assassin from his country.

Mannix is able to escape from a desert dinner being held by gunmen, only to return with the law and find the couple running it, deny any such incident happened.

Mannix thinks his traffic reporter friend saw something that made his killers shoot down his helicopter.

Mannix is skeptical of a little girl's claims of overhearing a murder plot, until it becomes clear someone wants her dead.

Mannix becomes less skeptical when a woman predicts from a dream he will be killed, when other things she described start happening to him.

A woman hires Mannix because she was followed from Hong Kong by a man, after her husband seemingly committed suicide over a shady deal over there.

A man is murdered after asking Mannix to find out who's harassing his wife, but Mannix discovers she's unaware of any such suspect.

After suffering recent memory loss in a fall while being chased, Mannix slowly begins to remember a woman being thrown to her death.

Mannix investigates why his cop friend, who served time for a crime he did not commit, killed his former cellmate and fled with $150,000 in stolen money.

Tough L.A. police Lt. Ira Deegan is warned off the investigation of a heist that netted $85,000 -- a threat that seems to have come true when his garage is blown up, although no one is hurt. Then Joe Mannix begins investigating the theft, which he claims is for the $8,500 recovery fee offered by the insurance company that would have to pay off on the theft. But Mannix' client is actually someone who is worried about Deegan's safety -- namely, his wife.

A married couple is scared into silence by a gangster who they saw run down his girlfriend, but their young boy tries to hire Mannix for help.

Mannix is at his college football team's reunion in a ghost town when members start getting murdered and a teammate that did not show up, is suspected.

Joe Mannix is hired by a secretive businessman named Alton K. Moore, who wants Mannix to look for his son Cal, a college basketball player who has been missing for several days. Although the case takes Mannix back to his alma mater, he has his doubts about Moore, who insists on meeting in remote places instead of at his office. His concerns about the elder Moore -- and the serious trouble that Cal may be in -- begin to seem justified when several thugs begin shadowing Mannix during his search.

Mannix investigates death threats against a young woman that had a car accident that killed her pregnant friend and left her legs paralyzed.

A somewhat ditsy heiress named Cindy Conrad comes by Mannix' office one evening, complaining that a mysterious woman has been phoning her to offer important information about the death of Conrad's father several years before. Mannix correctly guesses that the caller wants a large sum of money to provide the information. He tries to convince Conrad to ignore the calls -- but he begins to believe that something is wrong when someone takes a shot at them as he is escorting Conrad to her car.

Joe Mannix receives an urgent letter from a woman named Lynn Sargent asking him to fly to Arizona. She meets him at the airport and hands him a check for $1,000 and a small sealed package, telling him the money is his fee to take the package to the Los Angeles Police Department. Just as she does so, two men try to take the package, but Mannix manages to retain it after a scuffle. But the mystery deepens when the package turns out to contain nothing but blank sheets of paper -- and the police chief in the town tells Mannix that Lynn Sargent died a month earlier in a ...

Mannix tries to prove his ex-cop friend was not murdered by a serial killer, but killed because he knew about a killing wrongly blamed on the murderer.